ACE2 and COVID-19: It elaborately emphasizes on the different potential therapeutic options that could be pursued for therapy despite limited knowledge of the biology of SARS-CoV-2 such as neutralizing antibodies, oligonucleotides, passive antibody transfer, and drug repurposing, anti-viral proteases, blocking Coronavirus receptors like an angiotensin-converting enzyme (ACE2), combination therapy, which can bring a revolutionary change to curb the SARS-CoV-2/COVID-19 in the coming future [35, 36].