And our data showed that the tumor volume in nude mice treated with LINC00301 OE was markedly increased than that of in CTL group (Additional file 1: Figs. S13A–B), while LINC00301 OE plus EZH2 KD significantly repressed tumor growth derived in nude mice when compared with LINC00301 OE group (Additional file 1: Figs. S13A–B). Here, EZH2 is linked to neoplasm.