In our control outcome and yet unpublished work, we observed similar sex differences in associations between bilirubin, predicted by the same UGT1A1 SNP, and risk of pancreatic cancer (suggestive positive association in men and null association in women) using data of genetic consortia on pancreatic cancer (Supplementary Table 5, see Additional file 1). This evidence concerns the gene UGT1A1 and pancreatic neoplasm.