UGT1A1 and colorectal carcinoma: In contrast, Jiraskova et al. [17] reported an inverse association between the UGT1A1*28 polymorphism and CRC risk in men (OR = 0.75, 95% CI = 0.58–0.96) and also a non-significant inverse association in women (OR = 0.88, 95% CI = 0.66–1.18), which however may have limited generalizability due to a highly selected study sample.