VSMCs isolated from AAA patients showed altered DNA methylation levels found in four genes: v-ets avian erythroblastosis virus E26 oncogene homolog (ERG) with 13 hyper-methylated CpGs, IL-6 receptor (IL-6R) with 2 hyper-methylated CpGs, SMYD2 with 4 hypomethylated CpGs, and SERPINB9 with 6 hypo-methylated CpGs. This evidence concerns the gene SERPINB9 and triple-A syndrome.