Animals with early stress of MS showed a significant reduction in acetylated histone H3 level of GR promoter 17 at young (1.00 ± 0.05 vs. 0.76 ± 0.13; t = 2.206, p = 0.017) and middle adulthood (1.00 ± 0.11 vs. 0.28 ± 0.09; t = 13.460, p < 0.001, Figure 4A). Here, NR3C1 is linked to myeloid sarcoma.