After adjusting for age, sex, the presence of hypertension and diabetes mellitus, and SBP (Model 1), the obese group exhibited higher risk for severe MME (OR = 2.066, 95% CI 1.227–3.478, p = 0.006) and lower risk for mesangial C3 deposition (OR = 0.544, 95% CI 0.365–0.810, p = 0.003). This evidence concerns the gene C3 and diabetes mellitus.