The ARID1A-low HCC subtype was significantly associated with the NCI high-proliferation subtype (NCIP A), the hepatic stem cell (HS) subtype, the silence of Hippo pathway (SOH) subtype, and the high-recurrence (SNUR high) subtype (all, p < 0.001). This evidence concerns the gene ARID1A and hepatocellular carcinoma.