HGF and lung adenocarcinoma: It was found that HGF induced the expression of PD‐L1 in EGFR‐mutated NSCLC cells and regulated the proliferation and cytotoxicity of T lymphocytes: HGF not only activates the c‐MET signaling pathway in lung adenocarcinoma and induces drug resistance in EGFR‐TKIS151, 152 but also promotes the transcription of endogenous c‐MET genes.153