Study of TRIB3 expression in Oncomine database showed that TRIB3 was highly expressed in the many cancer group compared to the normal tissue group (Fig. 1c), for ovarian cancer ,TRIB3 was significantly highly expressed in 586 ovarian serous cyst adenocarcinomas compared with 8 normal ovarian tissues (Fig. 1d). The gene discussed is TRIB3; the disease is ovarian cancer.