In contrast, a number of genes found to be significantly mutated in other HCC cohorts (most notably AXIN1, ARID1A, ARID2, RPS6KA3, NFE2L2, and TERT, reported in at least half of the previous HCC studies here considered) do not appear significantly mutated in Mongolian HCC (Supplementary Data 11). The gene discussed is RPS6KA3; the disease is hepatocellular carcinoma.