SLC2A3 and colorectal carcinoma: To ascertain whether fuelling of these nucleotides by GLUT3-mediated glucose utilization is essential to promote CRC growth in vitro, we cultured HCT116 and SW620 cells with or without SLC2A3 silencing in medium supplemented with a nucleotide mixture containing adenosine, cytidine, guanosine and uridine (100 μM).