Compared with the control cells, CRC cells with ectopic GLUT3 expression exhibited increased rates of glucose uptake (Fig. 3c) and expedited glucose-induced cell proliferation (Fig. 3d), colony formation under low-glucose conditions (Fig. 3e) and accumulation of cells in the S phase of the cell cycle (Supplementary Fig. S4i). This evidence concerns the gene SLC2A3 and colorectal carcinoma.