GADD45B and esophageal cancer: Through transfection of siRNAs specific for MAP2K3 and GADD45B, as well as plasmids harboring full-length human MAP2K3 and GADD45B sequences (Supplementary Fig. S7A, B), we found MAP2K3 and GADD45B inhibited esophageal cancer cell proliferation (Supplementary Fig. S7C, D).