Early reports on the use of ACE inhibitors were inconsistent with studies suggesting they could be beneficial, harmful or have no effect in COVID-19 disease.14, –16 Sommerstein et al., postulated that ACE inhibitors may have a biphasic effect on patients with those taking this medication being more at risk of infection, but then more likely to have less severe disease.17 Our data give no good evidence of significant differences, but were under-powered to determine small differences. Here, ACE is linked to infection.