CXCL1 and neoplasm: Moreover, ADMA levels positively correlated with immune mediators known to support cancer development, the most strongly with GROα (CXCL1), the cytokine released from tumors as well as tumor-associated macrophages and implicated in the recruitment of tumor-associated neutrophils [31] and promotion of metastasis [32], respectively, and associated with poor overall survival [33].