STAT3 and neoplasm: Yu’s study showed that blocking STAT3 signaling with STAT3β or antisense STAT3 oligonucleotide activated dendritic cells (DCs) by inducing the proinflammatory mediators IL-6, regulated upon activation normal T cell expressed and secreted factor (RANTES) and interferon-inducible protein-10 (IP-10) in tumor cells [144].