Other studies assessing the risk of severe COVID-19 disease (defined based upon clinical and laboratory criteria) in ethnically homogenous cohorts have identified factors such as older age, LDH, CRP, RDW and direct bilirubin (DBIL), and blood urea nitrogen (BUN); and lower albumin (ALB) on admission, temperature, cough, dyspnea, hypertension, cardiovascular disease, chronic liver disease, and chronic kidney disease [18,19]. The gene discussed is CRP; the disease is chronic kidney disease.