Taking into account the metabolic effect of irisin and the induction of the effect of cryogenic temperatures on the secretion of this hormone in obese men, as shown in previous studies [26], and the induction of IL-6 secretion, without intensifying inflammation [33], we hypothesise that 20 WBC treatments reduce the content of adipose tissue and abdominal obesity in menopausal women, which is indirectly associated with an increase in the concentration of irisin and IL-6 in the blood. This evidence concerns the gene FNDC5 and Abdominal obesity.