The anticancer activity of cannabinoids, such as the inhibition of prolactin-induced proliferation, epidermal growth factor (EGF)-induced proliferation, and androgen-independent cancer cell invasion, frequently occurs due to various mechanisms, such as the inhibition of prolactin receptor expression, blocking cells at the G1/S checkpoint, and downregulating the production of EGF [29]. The gene discussed is EGF; the disease is cancer.