The human HT29 CRC cell line was isolated from a Dukes C stage tumor (with fat and lymph node invasion) and proved to be ideal to study mEHT effects on TP53 mutant (homozygous p.Arg273His (c.818G > A) cancer with deregulated canonical apoptosis induction [60]. The gene discussed is TP53; the disease is colorectal carcinoma.