EDN1 and infection: We noted a strong upregulation of genes encoding for CXCL2, CXCL3, CXCL10, IFNβ-1, IFNλ-1, -2, -3, endothelin 1 (EDN1) and IFIT-1, -2, -3 following E-30 infection (Figure 7A, Supplemental Table S1).