Genes with potential roles in lymphoproliferation were also concordantly regulated in SS and L-HES, including increased expression of CDCA7, DNM3 and TNFSF11, and decreased expression of SATB1. SATB1 can sensitize SS cells to activation induced cell death [72], and low expression of SATB1 is an independent prognostic factor in CTCL [89]. Here, SATB1 is linked to primary cutaneous T-cell non-Hodgkin lymphoma.