Methylation patterns of the VDR gene promoter regions were examined in normal human HSPCs (CD34-positive cells), mononuclear cells from UCB, and in mononuclear cells from peripheral blood (PB) (Figure 3b), leukemic cell lines (Figure 3c), and AML patients (Figure 3d) using bisulfite sequencing. Here, CD34 is linked to acute myeloid leukemia.