Remarkably, NGB treatment lowers oxidative stress upon H2O2 (400 μM; 30 min) stimulation, and PARP-1 cleavage under DTX treatment (100 nM; 48 h) in all breast cancer cell lines considered (Figure 4), although significant effects were observed at higher globin concentrations than in MCF-7 cell lines. The gene discussed is PARP1; the disease is breast carcinoma.