By preventing the tyrosine phosphorylation of STAT5, pimozide can decrease the expression of STAT5 target genes in KU812 and KU562 cells, such as Bcl-x, Pim-1, CIS, MCL-1 and cyclin D1, and reduce cell viability as well as induce apoptosis of the tumour cells [105]. This evidence concerns the gene STAT5B and neoplasm.