Moreover, evidence from Hu et al. shown that PCA at 25 μM concentration has significantly inhibited vascular endothelial growth factor (VEGF)-induced cell proliferation of human umbilical vein endothelial cell (HUVECs) by 22.68 ± 5.6% assessed by an MTT assay which further suggested PCA as a candidate treatment for cancer tumors [23]. The gene discussed is VEGFA; the disease is cancer.