Inverse correlations were also observed between the levels of 8 molecules (leptin, 5 cytokines, 2 chemokines) and blood counts of neutrophils (negative correlation with leptin in PV), monocytes (negative correlation with leptin, IL-8 and MIP-1β in PMF), lymphocytes (negative correlation with MIP-1α and MIP-1β in PMF) and platelets (negative correlation with TGF-β1 in ET) (Table 3). The gene discussed is CXCL8; the disease is essential thrombocythemia.