In addition, we checked GPER1 tendency of overexpression in RNA-Seq data from the Aging, Dementia, and Traumatic Brain Injury Study (http://aging.brain-map.org/), which confirmed its overexpression in dementia patients in comparison with healthy individuals (Wilcox Test p-value = 6.0 × 10−8). The gene discussed is GPER1; the disease is dementia.