For TC levels, univariate analysis showed that post-chemotherapy elevated TC levels were statistically associated with postmenopausal status, age > 40 years old, BMI > 24, ER negative, preoperative hypertension, and anthracycline-plus-taxane-based regimens (AC-T and EC-T) (P < .05). The gene discussed is ESR1; the disease is hypertensive disorder.