AKT1 and laryngeal carcinoma: Experiments conducted in vitro and in vivo demonstrated that SM‐BFRE could induce apoptosis in laryngeal carcinoma cells, and further verified that its anti‐laryngeal cancer effect that involved activation of the mitochondrial apoptotic pathway and inhibition of the STAT3 and Akt/NF‐κB signalling pathways (Figure 7).