TH and Huntington disease: Because neurochemical pathology and neuron loss in globus pallidus, substantia nigra and subthalamic nucleus (STN) occur and may also contribute to HD symptoms (Reiner, Dragatsis, & Dietrich, 2011; Vonsattel, 2008), we also characterized their pathology in the Q175 mice, using ISHH and immunolabeling for parvalbumin (PARV) in GPe, GPi and SNr, FoxP2 immunolabeling of GPe arkypallidal neurons, tyrosine hydroxylase immunolabeling of SNc dopaminergic neurons, and cresyl violet staining of STN neurons.