Among striatal interneurons, the tonically active large cholinergic interneurons (TANs) and the low threshold spiking (LTS) interneurons co‐containing somatostatin (SS), neuropeptide Y (NPY), and neuronal nitric oxide synthase (nNOS) survive the HD disease process, while the fast‐spiking GABAergic interneurons (FSIs) containing parvalbumin (PARV+) are largely as vulnerable as iSPNs (Reiner, Dragatsis, & Dietrich, 2011; Reiner et al., 2013). This evidence concerns the gene NOS1 and Huntington disease.