GRIA2 and Dystonia: Consistent with a role of PARV+ striatal interneuron deficiency in at least some forms of dystonia, Gittis et al. (2011) showed that infusion of IEM‐1460 (an inhibitor of the GluA2‐lacking AMPA receptors characteristic of FSIs) into mouse sensorimotor striatum, which selectively blocks synaptic excitation of PARV interneurons, elicits dystonia‐like movements.