TANGO2 and chronic obstructive pulmonary disease: Similarly, variants in TANGO2 (OMIM 616878) have been associated with recurrent metabolic encephalomyopathic crises with rhabdomyolysis, cardiac arrhythmias, and neurodegeneration, resulting due to vesicular Golgi‐ER transport and an increased ER stress, highlighting the importance of maintaining proper intracellular organelle crosstalk.27, 28