When the analysis was limited to molecular subtypes, high expression of DKC1 nuclear protein was significantly associated with poor outcome in ER+ high proliferation tumours (HR = 4.4, 95% CI = 1.6–12.3; p = 0.002), HER2+ tumours (HR = 2.6, 95% CI = 1.1–6.7; p = 0.039) and TNBC (HR = 1.5, 95% CI = 1.1–6.2; p = 0.035) Fig. 3d–g. The gene discussed is DKC1; the disease is neoplasm.