Alawi et al. have demonstrated that dyskerin expression peaks during G2/M and loss of dyskerin function has a widely disruptive effect on mitosis and triggers the spindle-assembly checkpoint.13 Our findings showed that high DKC1 expression was significantly associated with proliferation as assessed by Ki67 labelling index, which was also observed in other studies in BC52 hepatocellular carcinoma15 and prostate cancer,19 confirming that DKC1 is critical for mitotic progression and proliferation in these cancers. Here, MKI67 is linked to prostate cancer.