SOD1 and acute kidney injury: We also found that the protein levels of SOD1 and catalase were decreased (Fig. 6A) and the MDA levels (Fig. 6B) were increased in the kidneys of AKI mouse model, which could be significantly reversed by LIPUS treatment (Fig. 6; 47.1% increase in SOD1, 45.7% increase in catalase, 39.2% reduction in MDA).