The presence of ARID1A loss-of-function mutations was significantly associated with the loss of ARID1A protein expression in clear cell carcinomas (P < 0.001) (Fig. 4A) and the representative ARID1A staining images correspond to four patterns on the basis of ARID1A mutations and ARID1A protein expression (Fig. 4B). Here, ARID1A is linked to clear cell adenocarcinoma.