Thus, the results that ABHD4 is a proapoptotic molecule whose expression rapidly disappears in daughter neuroblasts and coincidentally, that ABHD4 downregulation in immortalized prostate epithelial cells prevents cell death28 together raise the intriguing possibility that a similar mechanism underlies anoikis resistance in healthy migrating neurons and in metastatic cancer cells. Here, ABHD4 is linked to metastatic malignant neoplasm.