Nonetheless, a band corresponding to an occludin fragment of 55 kDa (detected with an antibody against the C-terminal region of the protein) was detected in the cerebellum of MJD mice, while barely detected in wild-type animals (Fig. 5b), suggesting that occludin probably suffers exaggerated cleavage in MJD animals. Here, OCLN is linked to Spinocerebellar ataxia type 3.