TLR4 and Hepatic fibrosis: Post-transcriptional suppression of TLR4 expression by let-7i has been shown to contribute to immune responses to C. parvum infection in cultured human cholangiocytes, and mu-miR-92a-2-5p, which targets TLR2, relieves Schistosoma japonicum-induced liver fibrosis [6, 24].