Hence, the objectives of this study were (i) to study changes in α7nAChR+Sca1+ cells in the bone marrow and lung during pneumonia, (ii) to determine whether transplantation of α7nAChR+Sca1+ cell-enriched BM-MNCs affects lung injury, (iii) to examine whether vagotomy has an impact on α7nAChR+VE-cadherin+ and VE-cadherin+p-Akt1+ cells, and (iv) to elucidate whether vagotomy affects α7nAChR+Sca1+VE-cadherin+p-Akt1+ cells in pneumonia mice. Here, CDH5 is linked to susceptibility to pneumonia measurement.