Similar temporal profiles were also observed in rhFGF21-treated MCAO mice, but the cell counts of infiltrated immune cells (Fig. 4e), macrophages (Fig. 4f), and CD68+ and CD86+ macrophages (Fig. 4g, h) that accumulated in CNS were significantly decreased in rhFGF21-treated MCAO mice compared with the vehicle-treated MCAO mice at 3 days and 7 days after stroke. This evidence concerns the gene CD68 and Stroke.