Overexpression of the TAP1 protein has been suggested as an indicator of aggressiveness in breast cancers, which is thought to be due either to a lower capacity of more advanced tumors to downregulate TAP, or to a higher concentration of immune infiltrates in the microenvironment producing IFN-γ, which causes upregulation of the TAP subunits [18]. Here, TAP1 is linked to breast cancer.