CDH1 and neoplasm: Moreover, FadA promotes E-cadherin-mediated CRC tumor growth in xenograft mice via NF-κB activation, producing proinflammatory cytokines such as IL-6, IL-8, and IL-18 and upregulation of Wnt signaling gene (Wnt-7a, -7b, and -9a), Myc, and Cyclin D1 [15].