Of the proteins analysed here that showed significantly different levels in the combined analysis, 5 overlap with the KEGG “pancreatic cancer” pathway (NF-kappa-B essential modulator (NEMO), Pro-epidermal growth factor (EGF), Cyclin-dependent kinase inhibitor 1 (DKN1A), Vascular endothelial growth factor A (VEGF-A) and Transforming growth factor beta-1 (TGF-beta-1)). The gene discussed is IKBKG; the disease is familial pancreatic carcinoma.