The serum levels of CXCR4 (p = 0.01 OR = 1.228), CXCR2 (p = 0.01, OR = 5.816), the well-established tumor marker–CEA (p = 0.01, OR = 1.684) and CRP (p = 0.01, OR = 1.493) as well as patients age (p < 0.001, OR = 1.137) were associated with a significantly increased prediction of PC. Here, CEACAM5 is linked to neoplasm.