In the library prepared from ovarian tumor tissue (Table 2), 5 clones with coding sequences were identified using the HMGB1 bait (C1QA, DAG1, RPL29, RSF1, TGM2), and 6 (COMMD1, MIEN1, PCBP1, TBC1D25, ZFR, ZNF428) were identified with the HMGB2 bait. The gene discussed is TBC1D25; the disease is ovarian neoplasm.