Interestingly, we have shown in our study that HMGB1, HMGB2 and their EOC-HMGB-interactome partners MIEN1 and NOP53 are involved in the response to carboplatin, or drugs nowadays used in ovarian cancer treatment, such as bevacizumab, olaparib and paclitaxel. The gene discussed is HMGB1; the disease is ovarian carcinoma.