NR4A3 and acinar cell carcinoma: We identified fusion reads that mapped upstream of the NR4A3 gene on chromosome 9 in 16 of the 21 (76%) AcCC tumors (Table S2), all of which expressed high levels of NR4A3. As summarized in Figure 1A, the fusion reads identified a cluster of putative translocation breakpoints focused within a few kilobases upstream of the NR4A3 gene.