Interestingly, in one sample we instead identified fusion reads that mapped upstream of the related NR4A2-gene and that sample overexpressed NR4A2 instead of NR4A3. Two of the AcCC samples that contained fusion reads mapping to the NR4A3 gene also had some fusion reads that mapped to the nearby MSANTD3 gene, and those samples overexpressed both MSANTD3 and NR4A3. As shown in Figure 1A, NR4A3 and MSANTD3 are located in the same region of chromosome 9, suggesting that, at least in some AcCC samples, chromosomal translocations may lead to the aberrant activation of both genes. The gene discussed is NR4A2; the disease is acinar cell carcinoma.