Recent studies have demonstrated protective effects of HDAC inhibition by anti-inflammation and inhibition of proapoptotic factors in acute treatment of focal cerebral ischemia model of rats (1–6 h after stroke) with various compounds including valproic acid, trichostatin A and sodium butyrate [64,65,66,67,68,69,70,71,72,73]. Here, HDAC9 is linked to Stroke.