While JAK1 shows only marginal expression in A549 cells, there was a clear activation of JAK2 (phosphorylation of JAK2 at Y1007/Y1008) and its downstream target signal transducer and activator of transcription 3 (STAT3, phosphorylation at Y705) detectable upon WSN infection (Fig 1F). The gene discussed is STAT3; the disease is infection.