As per the inclusion criteria, all patients were in New York Heart Association functional class II to III with previous echocardiographic evidence of HF with left ventricular ejection fraction <50% (47.8% had an ejection fraction of 36% to 45%), with a median NT-proBNP of 2381 pg/mL (range, 1472–7434). Here, NPPB is linked to hydrops fetalis.