This variant was discovered in the most recent PD risk GWAS (OR, 0.94; SE, 0.0097; P = 1.13 × 10−10),3 and the closest gene is MED12L. The locus zoom plot showed a clear GWAS signal for this region (Fig. 2A); however, no genes in this locus were prioritized using current methods in the PD risk GWAS. The gene discussed is MED12L; the disease is Parkinson disease.