TIMP1 and abdominal aortic aneurysm: The C allele of the 372T/C polymorphism was more frequently found in female than male controls.[45] However, in other studies, the C allele was detected more frequently in male patients with an abdominal aortic aneurysm.[46] Meijer et al investigated the male subjects with inflammatory bowel disease carrying TIMP-1 (rs4898) T allele.